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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732196
Species: Homo sapiens
RGD Object: Gene
Symbol: FOSL1
Name: FOS like 1, AP-1 transcription factor subunit
Acc ID: CHEBI:7735
Term: olanzapine
Definition: A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4.
Chemical ID: MESH:C076029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FOSL1multiple interactionsISOFosl1 (Rattus norvegicus)6480464CTDolanzapine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOSL1 protein]PMID:11425506
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