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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732185
Species: Mus musculus
RGD Object: Gene
Symbol: Stat1
Name: signal transducer and activator of transcription 1
Acc ID: CHEBI:2618
Term: amantadine
Definition: A member of the class of adamantanes that is used as an antiviral and antiparkinson drug.
Chemical ID: MESH:D000547
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat1multiple interactionsISOSTAT1 (Homo sapiens)6480464CTD[Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1PMID:15918519
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