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GENE - TERM ANNOTATION REPORT

RGD ID: 732079
Species: Mus musculus
RGD Object: Gene
Symbol: Plat
Name: plasminogen activator, tissue
Acc ID: DOID:3525
Term: middle cerebral artery infarction
Definition: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Definition Source(s): MESH:D020244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plat ISOPlat (Rattus norvegicus)1580876RGD  
Plat ISOPLAT (Homo sapiens)11554173CTDCTD Direct Evidence: therapeuticPMID:12297567 PMID:17690543 PMID:18453163 PMID:20547619 PMID:29651748
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