GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk4 | decreases expression | EXP | | 6480464 | CTD | troglitazone results in decreased expression of CDK4 protein | PMID:15610522 | Cdk4 | decreases expression | ISO | CDK4 (Homo sapiens) | 6480464 | CTD | troglitazone results in decreased expression of CDK4 mRNA; troglitazone results in decreased expression of CDK4 protein | PMID:19140230 PMID:20540935 | Cdk4 | multiple interactions | ISO | CDK4 (Homo sapiens) | 6480464 | CTD | [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein]; GSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CDK4 protein] | PMID:20540935 | | ||||||||||||||||||||||
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