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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732055
Species: Mus musculus
RGD Object: Gene
Symbol: P2ry6
Name: pyrimidinergic receptor P2Y, G-protein coupled, 6
Acc ID: CHEBI:17659
Term: UDP
Definition: A pyrimidine ribonucleoside 5'-diphosphate that has formula C9H14N2O12P2.
Chemical ID: MESH:D014530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2ry6affects response to substanceEXP 6480464CTDP2RY6 gene affects the susceptibility to Uridine DiphosphatePMID:18523137
P2ry6multiple interactionsEXP 6480464CTDP2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]PMID:18523137
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