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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732028
Species: Homo sapiens
RGD Object: Gene
Symbol: NR4A2
Name: nuclear receptor subfamily 4 group A member 2
Acc ID: CHEBI:2208
Term: purine-6-thiol
Definition: A thiol that is the tautomer of mercaptopurine.
Chemical ID: MESH:D015122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR4A2increases expressionISONr4a2 (Rattus norvegicus)6480464CTDMercaptopurine results in increased expression of NR4A2 mRNAPMID:27435855
NR4A2multiple interactionsISONr4a2 (Rattus norvegicus)6480464CTD[GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 mRNA; [GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 protein; Mercaptopurine results in increased expression of and affects the localization of NR4A2 proteinPMID:27435855
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