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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731957
Species: Mus musculus
RGD Object: Gene
Symbol: Grm1
Name: glutamate receptor, metabotropic 1
Acc ID: CHEBI:145121
Term: SKF-96365 hydrochloride
Definition: The hydrochloride salt of SKF-96365. It is a TRP channel blocker.
Chemical ID: MESH:C063159
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grm1multiple interactionsISOGrm1 (Rattus norvegicus)6480464CTD1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]PMID:14622174
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