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GENE - TERM ANNOTATION REPORT

RGD ID: 731911
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: DOID:850
Term: lung disease
Definition: A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide. (DO)
Definition Source(s): http://www.niehs.nih.gov/health/topics/conditions/lung-disease/index.cfm "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000066.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9 IMP 5130156RGDVentilator-Induced Lung Injury 
Mmp9 ISOMMP9 (Homo sapiens)5129490RGDprotein:increased expression:bronchoalveolar lavage fluid 
Mmp9 ISOMmp9 (Rattus norvegicus)5129531RGDlung injury; mRNA, protein:increased expression:lung 
Mmp9 ISOMmp9 (Rattus norvegicus)5129548RGDlung injury associated with pancreatitis, acute necrotizing 
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