GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | increases expression | EXP | | 6480464 | CTD | Paraquat results in increased expression of MMP9 mRNA; Paraquat results in increased expression of MMP9 protein | PMID:17215068 PMID:21765237 PMID:23603004 PMID:25945502 PMID:26758514 PMID:26988026 PMID:30744607 PMID:32462952 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; Dapsone inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; naringin inhibits the reaction [Paraquat results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; Xuebijing inhibits the reaction [Paraquat results in increased expression of MMP9 protein] | PMID:21765237 PMID:23603004 PMID:25945502 PMID:26758514 PMID:30744607 PMID:32462952 | Mmp9 | decreases expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | Paraquat results in decreased expression of MMP9 mRNA | PMID:32680482 | Mmp9 | increases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Paraquat results in increased expression of MMP9 mRNA | PMID:22230393 | Mmp9 | increases expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | Paraquat results in increased expression of MMP9 mRNA; Paraquat results in increased expression of MMP9 protein | PMID:18630695 PMID:21468558 PMID:25233898 PMID:25873302 PMID:30726711 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | [CCN2 protein co-treated with Paraquat] affects the expression of MMP9 mRNA | PMID:26129822 | Mmp9 | multiple interactions | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | Febuxostat inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; Losartan inhibits the reaction [Paraquat results in increased expression of MMP9 mRNA] | PMID:25233898 PMID:30726711 | |
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