GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | decreases expression | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in decreased expression of MMP9 mRNA | PMID:19191707 | Mmp9 | increases activity | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased activity of MMP9 protein | PMID:19837106 | Mmp9 | increases expression | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased expression of MMP9 mRNA; 4-hydroxy-2-nonenal results in increased expression of MMP9 protein | PMID:19191707 PMID:19837106 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; MK-886 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]; U 75302 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein] | PMID:19837106 | | ||||||||||||||||||||||
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