GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | increases expression | EXP | | 6480464 | CTD | Mechlorethamine results in increased expression of MMP9; Mechlorethamine results in increased expression of MMP9 protein | PMID:24631667 PMID:25891025 PMID:30060251 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of MMP9]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MMP9 protein] | PMID:24631667 PMID:30060251 | Mmp9 | increases expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | Mechlorethamine results in increased expression of MMP9 mRNA; Mechlorethamine results in increased expression of MMP9 protein | PMID:20883710 PMID:26273949 PMID:28184907 | Mmp9 | multiple interactions | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of MMP9 mRNA] | PMID:28184907 | | ||||||||||||||||||||||
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