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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731911
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:15354
Term: choline
Definition: A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Chemical ID: MESH:D002794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9multiple interactionsEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 protein]; [Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MMP9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of MMP9 protein]; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 protein; NLRP3 protein affects the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of MMP9 protein]]; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 mRNA]PMID:22915297 PMID:23439872 PMID:28973532 PMID:34416350
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