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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731900
Species: Homo sapiens
RGD Object: Gene
Symbol: SEMA6B
Name: semaphorin 6B
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SEMA6Bdecreases expressionEXP 6480464CTDFenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B proteinPMID:16525649
SEMA6Bmultiple interactionsEXP 6480464CTDalitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein]PMID:16525649
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