GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cga | multiple interactions | EXP | | 6480464 | CTD | [ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]; ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP] | PMID:20378682 | Cga | affects secretion | ISO | CGA (Homo sapiens) | 6480464 | CTD | CGA protein affects the secretion of Cyclic AMP | PMID:23071612 | Cga | increases abundance | ISO | CGA (Homo sapiens) | 6480464 | CTD | CGA protein results in increased abundance of Cyclic AMP | PMID:20378682 PMID:21642635 PMID:31132478 PMID:33638691 | Cga | multiple interactions | ISO | CGA (Homo sapiens) | 6480464 | CTD | [CGA protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [CGA protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Cyclic AMP; [CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; Cyclic AMP inhibits the reaction [[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]]; DDT inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP] | PMID:20378682 PMID:23071612 PMID:26895433 PMID:33638691 PMID:37552060 | Cga | multiple interactions | ISO | Cga (Rattus norvegicus) | 6480464 | CTD | [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of CGA mRNA | PMID:8404651 | | ||||||||||||||||||||||
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