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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731748
Species: Homo sapiens
RGD Object: Gene
Symbol: JAK2
Name: Janus kinase 2
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JAK2increases phosphorylationEXP 6480464CTDOxygen deficiency results in increased phosphorylation of JAK2 proteinPMID:29685624
JAK2multiple interactionsEXP 6480464CTDalpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide promotes the reaction [Folic Acid inhibits the reaction [Oxygen deficiency results in increased phosphorylation of JAK2 protein]]; Folic Acid inhibits the reaction [Oxygen deficiency results in increased phosphorylation of JAK2 protein]PMID:29685624
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