GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp1 | increases cleavage | EXP | | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased cleavage of CASP1 protein | PMID:25929181 | Casp1 | increases expression | EXP | | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased expression of CASP1 protein | PMID:31070765 | Casp1 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Toluene 2,4-Diisocyanate results in increased cleavage of CASP1 protein]; belnacasan inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CASP1 protein]; L 709049 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CASP1 protein] | PMID:25929181 PMID:31070765 | | ||||||||||||||||||||||
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