GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp1 | increases expression | ISO | CASP1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of CASP1 mRNA | PMID:23452621 | Casp1 | multiple interactions | ISO | Casp1 (Rattus norvegicus) | 6480464 | CTD | [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CASP1 mRNA]; [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CASP1 protein]; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CASP1 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CASP1 protein; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP1 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP1 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein modified form; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein modified form]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP1 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP1 protein] | PMID:26464617 PMID:33729688 PMID:35191607 | Casp1 | multiple interactions | ISO | CASP1 (Homo sapiens) | 6480464 | CTD | 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein; bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]; Genistein inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]; Plant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA] | PMID:23452621 PMID:37127800 | | ||||||||||||||||||||||
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