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GENE - TERM ANNOTATION REPORT

RGD ID: 731713
Species: Mus musculus
RGD Object: Gene
Symbol: Vamp8
Name: vesicle-associated membrane protein 8
Acc ID: GO:0031201
Term: SNARE complex
Definition: A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
Definition Source(s): GOC:bhm, GOC:pr, PMID:10872468, PMID:19450911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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