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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731517
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c70
Name: cytochrome P450, family 2, subfamily c, polypeptide 70
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c70decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CYP2C70 mRNAPMID:29161229
Cyp2c70increases expressionEXP 6480464CTDbisphenol A results in increased expression of CYP2C70 mRNAPMID:30245210 PMID:33221593
Cyp2c70multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP2C70 mRNAPMID:28433925
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