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GENE - TERM ANNOTATION REPORT

RGD ID: 731493
Species: Mus musculus
RGD Object: Gene
Symbol: Cdc25a
Name: cell division cycle 25A
Acc ID: GO:0000086
Term: G2/M transition of mitotic cell cycle
Definition: The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
Definition Source(s): GOC:mtg_cell_cycle
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdc25ainvolved_inIBAPANTHER:PTN0000890712290270GO_Central MGI:6201960 PMID:21873635

MGI:6201960 PMID:21873635
Cdc25ainvolved_inISOUniProtKB:P303042290270MGI GO_REF:0000119 MGI:4834177
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