GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp2 | decreases expression | ISO | CASP2 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased expression of CASP2 protein | PMID:18089832 | Casp2 | increases expression | ISO | CASP2 (Homo sapiens) | 6480464 | CTD | resveratrol results in increased expression of CASP2 mRNA | PMID:25436977 PMID:25667456 PMID:29242151 | Casp2 | multiple interactions | ISO | CASP2 (Homo sapiens) | 6480464 | CTD | [resveratrol co-treated with TNFSF10 protein] results in increased activity of CASP2 protein; CASP2 protein affects the reaction [resveratrol affects the folding of BAK1 protein]; CASP2 protein affects the reaction [resveratrol affects the folding of BAX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]; resveratrol results in increased cleavage of and results in increased activity of CASP2 protein; SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]]; SUMO1 protein affects the reaction [resveratrol results in increased expression of CASP2 mRNA] | PMID:15763656 PMID:16617056 PMID:29242151 | | ||||||||||||||||||||||
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