GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SYN1 | affects response to substance | ISO | Syn1 (Mus musculus) | 6480464 | CTD | SYN1 protein affects the susceptibility to 4-Aminopyridine | PMID:22759588 | SYN1 | increases expression | ISO | Syn1 (Rattus norvegicus) | 6480464 | CTD | 4-Aminopyridine results in increased expression of SYN1 protein modified form | PMID:28132918 | SYN1 | increases response to substance | ISO | Syn1 (Mus musculus) | 6480464 | CTD | SYN1 results in increased susceptibility to 4-Aminopyridine | PMID:28132918 | SYN1 | multiple interactions | ISO | Syn1 (Rattus norvegicus) | 6480464 | CTD | [4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein; ciproxifan inhibits the reaction [4-Aminopyridine results in increased expression of SYN1 protein modified form]; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein] | PMID:28132918 PMID:33621091 | |
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