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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731420
Species: Homo sapiens
RGD Object: Gene
Symbol: VMP1
Name: vacuole membrane protein 1
Acc ID: CHEBI:27666
Term: actinomycin D
Definition: An actinomycin that has formula C62H86N12O16.
Chemical ID: MESH:D003609
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VMP1decreases expressionEXP 6480464CTDDactinomycin results in decreased expression of VMP1 mRNAPMID:23052036
VMP1multiple interactionsEXP 6480464CTD[Dactinomycin co-treated with fludioxonil] results in decreased expression of VMP1 mRNA; Dactinomycin inhibits the reaction [Dehydroepiandrosterone results in increased expression of VMP1 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of VMP1 mRNA]PMID:23052036 PMID:25969534
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