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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731411
Species: Homo sapiens
RGD Object: Gene
Symbol: STX8
Name: syntaxin 8
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STX8affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of STX8 intronPMID:30157460
STX8decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of STX8 mRNAPMID:20064835 PMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424
STX8decreases expressionISOStx8 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of STX8 mRNAPMID:19770486 PMID:21715664
STX8increases expressionISOStx8 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of STX8 mRNAPMID:22228805
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