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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731383
Species: Mus musculus
RGD Object: Gene
Symbol: Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kitdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KIT mRNAPMID:32156529
Kitdecreases expressionISOKit (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KIT mRNAPMID:24066056 PMID:25181051 PMID:30816183 PMID:32528016
Kitdecreases methylationISOKIT (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of KIT genePMID:31601247
Kitincreases expressionISOKit (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of KIT mRNAPMID:27208089 PMID:34947998
Kitincreases expressionISOKIT (Homo sapiens)6480464CTDbisphenol A results in increased expression of KIT mRNAPMID:37610061
Kitincreases methylationISOKit (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of KIT genePMID:28505145
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