Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 731081
Species: Homo sapiens
RGD Object: Gene
Symbol: PGR
Name: progesterone receptor
Acc ID: CHEBI:34211
Term: 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
Definition: A diarylmethane that has formula C14H8Cl4.
Chemical ID: MESH:C054919
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects bindingEXP 6480464CTD2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene binds to PGR protein

multiple interactionsEXP 6480464CTD2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene inhibits the reaction [Progesterone binds to PGR protein], 2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene inhibits the reaction [Progesterone results in increased expression of PGR protein]

PMID:14579009, PMID:18262749
Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.