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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731081
Species: Homo sapiens
RGD Object: Gene
Symbol: PGR
Name: progesterone receptor
Acc ID: CHEBI:34211
Term: 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
Definition: A diarylmethane that has formula C14H8Cl4.
Chemical ID: MESH:C054919
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects bindingEXP 6480464CTD2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene binds to PGR protein

PMID:14579009
multiple interactionsEXP 6480464CTD2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene inhibits the reaction [Progesterone binds to PGR protein], 2, 2-(2-chlorophenyl-4'-chlorophenyl)-1, 1-dichloroethene inhibits the reaction [Progesterone results in increased expression of PGR protein]

PMID:14579009, PMID:18262749
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