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GENE - TERM ANNOTATION REPORT

RGD ID: 731073
Species: Mus musculus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: GO:0001666
Term: response to hypoxia
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Definition Source(s): GOC:hjd
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfa ISOVegfa (Rattus norvegicus)9068941RGD PMID:12881220 REF_RGD_ID:1580563
Vegfainvolved_inIBAPANTHER:PTN000246442 or Vegfa (Rattus norvegicus) or Vegfd (Rattus norvegicus) or UniProtKB:P15691 or Pgf (Rattus norvegicus) or UniProtKB:P156922290270GO_Central GO_REF:0000033
Vegfainvolved_inISOVegfa (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
Vegfainvolved_inISOUniProtKB:P156922290270MGI GO_REF:0000119 MGI:4834177
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