GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | VEGFA | affects expression | EXP | | 6480464 | CTD | Folic Acid affects the expression of VEGFA mRNA | PMID:16361273 | VEGFA | increases expression | EXP | | 6480464 | CTD | Folic Acid results in increased expression of VEGFA mRNA | PMID:25841994 | VEGFA | multiple interactions | EXP | | 6480464 | CTD | [Ethanol co-treated with Folic Acid] results in increased expression of VEGFA mRNA; Folic Acid inhibits the reaction [dimethyloxallyl glycine results in increased expression of VEGFA mRNA]; Folic Acid inhibits the reaction [INS protein results in increased expression of VEGFA mRNA] | PMID:23378141 PMID:26974319 | VEGFA | decreases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Folic Acid results in decreased expression of VEGFA mRNA; Folic Acid results in decreased expression of VEGFA protein | PMID:14633603 PMID:25629700 | VEGFA | increases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Folic Acid results in increased expression of VEGFA protein | PMID:25912570 | VEGFA | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of VEGFA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of VEGFA gene; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VEGFA mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VEGFA protein]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the methylation of VEGFA promoter]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of VEGFA protein]; Folic Acid inhibits the reaction [Dexamethasone results in decreased expression of VEGFA mRNA] | PMID:20938992 PMID:24386282 PMID:25912570 PMID:28475147 | | ||||||||||||||||||||||
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