GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | VEGFA | increases expression | EXP | | 6480464 | CTD | Hydrogen Peroxide results in increased expression of VEGFA mRNA; Hydrogen Peroxide results in increased expression of VEGFA protein | PMID:12374620 PMID:20021702 PMID:36162953 | VEGFA | multiple interactions | EXP | | 6480464 | CTD | [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of VEGFA mRNA; [Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of VEGFA mRNA]]; epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of VEGFA protein]]; Grape Seed Extract promotes the reaction [Hydrogen Peroxide results in increased expression of VEGFA mRNA]; Grape Seed Extract promotes the reaction [Hydrogen Peroxide results in increased expression of VEGFA protein]; Quercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of VEGFA mRNA]; Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of VEGFA mRNA]; Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of VEGFA protein] | PMID:12374620 PMID:19910455 PMID:20021702 PMID:24489904 PMID:36162953 | VEGFA | increases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of VEGFA mRNA | PMID:17997286 | VEGFA | multiple interactions | ISO | Vegfa (Rattus norvegicus) | 6480464 | CTD | [3,4-dihydroxyphenylethanol co-treated with Hydrogen Peroxide] results in increased expression of VEGFA mRNA; [Sirolimus co-treated with Hydrogen Peroxide] results in increased expression of VEGFA mRNA; VEGFA protein affects the reaction [Copper results in decreased susceptibility to and results in decreased activity of Hydrogen Peroxide] | PMID:17327471 PMID:31332898 | VEGFA | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Sodium Selenite promotes the reaction [Hydrogen Peroxide results in increased expression of VEGFA mRNA] | PMID:17997286 | | ||||||||||||||||||||||
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