GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AHR | increases expression | EXP | | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of AHR mRNA | PMID:31326446 | AHR | multiple interactions | ISO | Ahr (Mus musculus) | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] | PMID:16601081 | AHR | multiple interactions | ISO | Ahr (Rattus norvegicus) | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether analog binds to and results in increased activity of AHR protein; 2,2',4,4'-tetrabromodiphenyl ether binds to and results in decreased activity of AHR protein; 2,2',4,4'-tetrabromodiphenyl ether binds to and results in increased activity of AHR protein; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] | PMID:12850102 PMID:16601080 PMID:16601081 | |
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