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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731071
Species: Homo sapiens
RGD Object: Gene
Symbol: AHR
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:35298
Term: anthracene
Definition: An ortho-fused tricyclic hydrocarbon comprising three fused benzene rings.
Chemical ID: MESH:C034020
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AHRaffects localizationEXP 6480464CTDanthracene affects the localization of AHR proteinPMID:19362136
AHRincreases activityEXP 6480464CTDanthracene results in increased activity of AHR proteinPMID:17665671
AHRmultiple interactionsEXP 6480464CTD2-oxohexyl isothiocyanate inhibits the reaction [anthracene affects the localization of AHR protein]; [acenaphthene co-treated with anthracene co-treated with 1,12-benzoperylene co-treated with 1,2,5,6-dibenzanthracene co-treated with fluorene co-treated with naphthalene co-treated with phenanthrene] results in increased activity of AHR protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein]; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein]; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein]; alyssin inhibits the reaction [anthracene affects the localization of AHR protein]; sulforaphane affects the reaction [anthracene affects the localization of AHR protein]PMID:17665671 PMID:19362136 PMID:28710019 PMID:30980910
AHRaffects bindingISOAhr (Rattus norvegicus)6480464CTDanthracene binds to AHR proteinPMID:3024361
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