GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AHR | affects localization | EXP | | 6480464 | CTD | sodium arsenite affects the localization of AHR protein | PMID:28189647 | AHR | affects methylation | EXP | | 6480464 | CTD | sodium arsenite affects the methylation of AHR gene | PMID:28589171 | AHR | increases activity | EXP | | 6480464 | CTD | sodium arsenite results in increased activity of AHR protein | PMID:19033395 | AHR | multiple interactions | EXP | | 6480464 | CTD | [sodium arsenite co-treated with Benzo(a)pyrene co-treated with Cadmium Chloride] results in increased activity of AHR protein; [sodium arsenite co-treated with Benzo(a)pyrene co-treated with lead acetate] results in increased activity of AHR protein; [sodium arsenite co-treated with Benzo(a)pyrene] results in increased activity of AHR protein; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [AHR protein binds to SUV39H1 promoter]; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [Benzo(a)pyrene affects the localization of AHR protein]; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to SUV39H1 promoter]]; [sodium arsenite results in increased abundance of Arsenic] which affects the localization of AHR protein; AHR mutant form promotes the reaction [sodium arsenite results in decreased expression of CYP1A1 protein]; AHR protein affects the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of SUV39H1 protein]; AHR protein affects the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Benzo(a)pyrene promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the localization of AHR protein] | PMID:19033395 PMID:24161444 PMID:29502740 PMID:32062438 | AHR | decreases expression | ISO | Ahr (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of AHR mRNA; sodium arsenite results in decreased expression of AHR protein | PMID:16014739 PMID:17682005 | | ||||||||||||||||||||||
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