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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731060
Species: Mus musculus
RGD Object: Gene
Symbol: Rhoa
Name: ras homolog family member A
Acc ID: CHEBI:15996
Term: GTP
Definition: A purine ribonucleoside 5'-triphosphate that has formula C10H16N5O14P3.
Chemical ID: MESH:D006160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rhoamultiple interactionsEXP 6480464CTDDronabinol inhibits the reaction [Guanosine Triphosphate binds to and results in increased activity of RHOA protein]; Guanosine Triphosphate binds to and results in increased activity of RHOA protein; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]; Zoledronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]PMID:16734383 PMID:29307655
Rhoaaffects bindingISORHOA (Homo sapiens)6480464CTDRHOA protein binds to Guanosine TriphosphatePMID:21257924
Rhoamultiple interactionsISORHOA (Homo sapiens)6480464CTDAsbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Cadmium Chloride promotes the reaction [RHOA protein binds to Guanosine Triphosphate]; Dronabinol inhibits the reaction [Guanosine Triphosphate binds to and results in increased activity of RHOA protein]; Guanosine Triphosphate binds to and results in increased activity of RHOA protein; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]; tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Zoledronic Acid results in increased expression of [RHOA protein binds to Guanosine Triphosphate]PMID:16734383 PMID:21257924 PMID:26220685 PMID:28871336 PMID:29307655
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