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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731056
Species: Homo sapiens
RGD Object: Gene
Symbol: INS
Name: insulin
Acc ID: CHEBI:15843
Term: arachidonic acid
Definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Chemical ID: MESH:D016718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
INSincreases secretionEXP 6480464CTDArachidonic Acid results in increased secretion of INS proteinPMID:17192482
INSmultiple interactionsEXP 6480464CTDArachidonic Acid promotes the reaction [Glucose results in increased secretion of INS protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]; phenidone promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]PMID:17192482
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