GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ephx2 | increases expression | EXP | | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of EPHX2 mRNA; Diethylhexyl Phthalate results in increased expression of EPHX2 protein | PMID:19850644 PMID:3318844 PMID:3621371 | Ephx2 | multiple interactions | EXP | | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of EPHX2 mRNA; PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of EPHX2 mRNA] | PMID:19850644 PMID:28433925 | Ephx2 | decreases expression | ISO | EPHX2 (Homo sapiens) | 6480464 | CTD | Diethylhexyl Phthalate results in decreased expression of EPHX2 mRNA | PMID:31163220 | |
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