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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731054
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHX2
Name: epoxide hydrolase 2
Acc ID: CHEBI:50006
Term: stilbene oxide
Definition: An epoxide that has formula C14H12O.
Chemical ID: MESH:C025906
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHX2increases metabolic processingISOEphx2 (Mus musculus)6480464CTDEPHX2 protein results in increased metabolism of stilbene oxide; EPHX2 protein results in increased metabolism of stilbene oxide analogPMID:2043152
EPHX2multiple interactionsISOEphx2 (Mus musculus)6480464CTD16 alpha,17-epoxyprogesterone inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; cholesterol alpha-oxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; ethylphenylepoxygeranyl ether promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Heptachlor Epoxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Heptachlor Epoxide promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Lanosterol analog inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; limonin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; nomilin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]PMID:2043152
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