GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BDNF | decreases methylation | ISO | Bdnf (Mus musculus) | 6480464 | CTD | Potassium Chloride results in decreased methylation of BDNF promoter | PMID:14593183 | BDNF | increases expression | ISO | Bdnf (Mus musculus) | 6480464 | CTD | Potassium Chloride results in increased expression of BDNF mRNA | PMID:14593183 | BDNF | multiple interactions | ISO | Bdnf (Mus musculus) | 6480464 | CTD | BDNF promoter modified form affects the reaction [Potassium Chloride results in increased expression of BDNF mRNA]; Potassium Chloride inhibits the reaction [HDAC1 protein binds to BDNF promoter]; Potassium Chloride inhibits the reaction [MECP2 protein binds to BDNF promoter]; Potassium Chloride inhibits the reaction [SIN3A protein binds to BDNF promoter]; Potassium Chloride promotes the reaction [CREB1 protein binds to BDNF promoter] | PMID:14593183 | | ||||||||||||||||||||||
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