GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccn2 | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of CCN2 protein | PMID:19280452 PMID:28962519 | Ccn2 | multiple interactions | EXP | | 6480464 | CTD | [Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA; [Ethanol results in increased expression of CCN2 protein] which results in increased abundance of Acetaldehyde; allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA]; allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 protein]; CAT protein inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA]; CAT protein inhibits the reaction [Ethanol results in increased expression of CCN2 protein]; Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA]; Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 protein]; Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA]; Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 protein] | PMID:19280452 PMID:21863215 | Ccn2 | decreases expression | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | Ethanol results in decreased expression of CCN2 mRNA | PMID:31059573 | Ccn2 | increases expression | ISO | Ccn2 (Rattus norvegicus) | 6480464 | CTD | Ethanol results in increased expression of CCN2 mRNA | PMID:16098508 | Ccn2 | multiple interactions | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CCN2 mRNA | PMID:29432896 | | ||||||||||||||||||||||
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