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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731007
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsEXP 6480464CTD2-tert-butylhydroquinone inhibits the reaction [Matrines results in increased expression of PTGS2 mRNA]PMID:37716422
Ptgs2multiple interactionsISOPtgs2 (Rattus norvegicus)6480464CTD2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of PTGS2 protein]PMID:28583816
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