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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731007
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:77986
Term: dibenziodolium
Definition: An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Chemical ID: MESH:C007517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsEXP 6480464CTDdiphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; diphenyleneiodonium inhibits the reaction [Endosulfan results in increased expression of PTGS2 mRNA]; diphenyleneiodonium inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]PMID:14687664 PMID:16024921 PMID:25199686
Ptgs2multiple interactionsISOPTGS2 (Homo sapiens)6480464CTDdiphenyleneiodonium inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]PMID:19804834 PMID:22288910
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