GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | multiple interactions | EXP | | 6480464 | CTD | Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased abundance of Dinoprostone]; Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] | PMID:12757841 PMID:16101137 PMID:20043298 | Ptgs2 | decreases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Eugenol results in decreased expression of PTGS2 mRNA | PMID:12757841 PMID:21939359 | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Eugenol results in increased expression of PTGS2 mRNA | PMID:30806763 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2] | PMID:20036707 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] | PMID:17509409 PMID:21807015 | | ||||||||||||||||||||||
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