GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | decreases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in decreased expression of PTGS2 mRNA | PMID:37019170 | Ptgs2 | increases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in increased expression of PTGS2 mRNA; Chlorpyrifos results in increased expression of PTGS2 protein | PMID:29709151 | Ptgs2 | increases expression | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Chlorpyrifos results in increased expression of PTGS2 protein | PMID:33908150 | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in increased expression of PTGS2 protein | PMID:23416140 PMID:24793810 PMID:32526215 PMID:34424684 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Hesperidin inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein] | PMID:33908150 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; [Meloxicam results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Chlorpyrifos; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; Fulvestrant promotes the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; Rosiglitazone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; SN50 peptide inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein] | PMID:23416140 PMID:24793810 PMID:32526215 PMID:34424684 | | ||||||||||||||||||||||
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