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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731007
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:34565
Term: benzo[b]fluoranthene
Definition: An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.
Chemical ID: MESH:C006703
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2decreases expressionISOPTGS2 (Homo sapiens)6480464CTDbenzo(b)fluoranthene results in decreased expression of PTGS2 proteinPMID:25956473
Ptgs2multiple interactionsISOPTGS2 (Homo sapiens)6480464CTD[Docosahexaenoic Acids co-treated with benzo(b)fluoranthene] results in increased expression of PTGS2 mRNAPMID:25956473
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