GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | increases expression | EXP | | 6480464 | CTD | Carrageenan results in increased expression of PTGS2 protein | PMID:26418808 | Ptgs2 | multiple interactions | EXP | | 6480464 | CTD | fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein] | PMID:26418808 | Ptgs2 | increases expression | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Carrageenan results in increased expression of PTGS2 mRNA; Carrageenan results in increased expression of PTGS2 protein | PMID:10101034 PMID:15860553 PMID:17258197 PMID:18814970 PMID:19735303 PMID:22198006 PMID:24337631 PMID:27803785 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | 3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; dragon's blood inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; nimesulide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; resveratrol inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Thioctic Acid inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; triflusal inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein] | PMID:10101034 PMID:14654164 PMID:15860553 PMID:17258197 PMID:18814970 PMID:19735303 PMID:22198006 PMID:24337631 PMID:27803785 | | ||||||||||||||||||||||
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