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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731007
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:2981
Term: baicalin
Definition: The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.
Chemical ID: MESH:C038044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2decreases expressionISOPtgs2 (Rattus norvegicus)6480464CTDbaicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 proteinPMID:22019745
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