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GENE - TERM ANNOTATION REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: DOID:9008443
Term: Colorectal Neoplasms
Definition: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Definition Source(s): MESH:D015179
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:10485483 PMID:11375891 PMID:12837940 PMID:15753380 PMID:19671906 PMID:20427397
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