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GENE - TERM ANNOTATION REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: DOID:9000117
Term: Esophageal Neoplasms
Definition: Tumors or cancer of the ESOPHAGUS.
Definition Source(s): MESH:D004938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2susceptibilityIAGP 5135528RGDDNA:SNPs: :-1195A > G, -765G > C (human) 
PTGS2 ISOPtgs2 (Rattus norvegicus)5687745RGDmRNA,protein:increased expression:Esophagus 
PTGS2 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:11059772 PMID:16322294 PMID:17707579
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