GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | decreases expression | EXP | | 6480464 | CTD | epigallocatechin gallate results in decreased expression of PTGS2 mRNA | PMID:16084531 | PTGS2 | increases expression | EXP | | 6480464 | CTD | epigallocatechin gallate results in increased expression of PTGS2 protein | PMID:15210717 | PTGS2 | multiple interactions | EXP | | 6480464 | CTD | 1-Butanol inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; epigallocatechin gallate inhibits the reaction [Glucose results in increased expression of PTGS2 protein]; Go 6976 inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; Go 6976 inhibits the reaction [PLD2 protein promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]]; PLD1 protein promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; PLD2 protein promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; Propranolol promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [PLD2 protein promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]] | PMID:15210717 PMID:19557821 | PTGS2 | increases expression | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | epigallocatechin gallate results in increased expression of PTGS2 protein | PMID:15210717 | PTGS2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | 1-Butanol inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PTGS2 protein]]; Go 6976 inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein] | PMID:15210717 PMID:29999212 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 mRNA]; epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] | PMID:20438794 PMID:23717041 | |
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