A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 protein]; [Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; aurapten inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; EGTA acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Piroxicam inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]; Tetrachlorodibenzodioxin promotes the reaction [EP300 protein binds to PTGS2 promoter]; Tetrachlorodibenzodioxin promotes the reaction [H4C16 protein modified form binds to PTGS2 promoter]; zerumbone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of PTGS2 protein; [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] which results in increased abundance of Dinoprostone; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; herbimycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPA protein binds to CEBPB protein] which binds to PTGS2 promoter]]; herbimycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [PTGS2 protein results in increased expression of CGA mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [PTGS2 protein results in increased expression of CGA protein]; Tetrachlorodibenzodioxin results in increased activity of [[CEBPA protein binds to CEBPB protein] which binds to PTGS2 promoter]; Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; [[Tetrachlorodibenzodioxin binds to AHR protein] which binds to PTGS2 promoter] which results in increased expression of PTGS2 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of PTGS2 mRNA; [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA; [Tetrachlorodibenzodioxin results in decreased expression of MIR101A] which results in increased expression of PTGS2 mRNA; [Tetrachlorodibenzodioxin results in decreased expression of MIR101A] which results in increased expression of PTGS2 protein; AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; AHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Arachidonic Acid affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PTGS2 protein]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Indomethacin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PTGS2 protein]; LTB4R1 mRNA promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 gene]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein results in increased expression of PTGS2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [EGR1 protein binds to PTGS2 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Vanadates promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; zerumbone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; zileuton inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]