A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID:
MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP3 protein; [Dexamethasone co-treated with Bortezomib] results in increased activity of CASP3 protein; [GCS-100 co-treated with Dexamethasone] results in increased activity of CASP3 protein; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [PDCD5 protein co-treated with Dexamethasone] results in increased expression of CASP3; Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Dexamethasone promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of CASP3 protein]; Dexamethasone promotes the reaction [Gold results in increased activity of CASP3 protein]; Dexamethasone promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Dexamethasone promotes the reaction [Silver results in increased activity of CASP3 protein]; Dexamethasone results in increased cleavage of and results in increased activity of CASP3 protein; FAS protein inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]; Ginkgo biloba extract inhibits the reaction [Dexamethasone results in increased expression of CASP3 protein]; isocoumarin NM-3 promotes the reaction [Dexamethasone results in increased activity of CASP3 protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]]
aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]; CDKN1A protein affects the reaction [Dexamethasone results in increased cleavage of CASP3 protein]; Dexamethasone inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]; MK 2206 inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]; naringin inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]; Spermine inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]
Active Hexose Correlated Compound inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]; caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]; Dexamethasone inhibits the reaction [Arsanilic Acid results in increased cleavage of CASP3 protein]; Dexamethasone inhibits the reaction [Arsanilic Acid results in increased expression of CASP3 mRNA]; Dexamethasone inhibits the reaction [Camptothecin results in increased activity of CASP3 protein]; Dexamethasone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Dexamethasone inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; Dexamethasone inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]; Dexamethasone results in increased cleavage of and results in increased activity of CASP3 protein; Dexamethasone results in increased expression of and results in increased cleavage of CASP3 protein; fludarabine inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in increased cleavage of CASP3 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in increased expression of CASP3 mRNA]]; Ubiquinone inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]
